52 weeks of tracking, January through now. Scale: 214 to 176. Waist: 38 to 33.5 in. Fasting insulin was 18 in January, now 17.2. Triglycerides 142 to 118. hs-CRP 2.8 to 1.9.
Appetite tends to shift around the three-week mark, and the scale moves in fits — first 24 weeks steady, weeks 30-40 almost flat, then 4 lb in three weeks. Curious if others track labs and tape, not just the scale.
I expected insulin to drop more given that much weight change. Is that lag common? What did your numbers do?
Your waist drop is bigger than mine at a similar scale change. Tape matters more than I thought.
How often are you testing? My fasting insulin bounced around 2-3 points depending on sleep and late meals.
I’ve tracked labs every 12 weeks since week 0. Weight fell fastest weeks 8-28, then stalled around week 36.
Waist kept shrinking during the stall. Triglycerides fell first, then hs-CRP.
Fasting insulin didn’t move much until week 48, and even then it was modest. The scale and labs didn’t line up neatly.
I stopped expecting them to move together.
I also noticed sleep and stress changed the morning numbers more than I liked. The only thing that tracked with insulin for me was waist and sleep, not the scale. Your week 52 insulin number isn’t weird to me.
The flat weeks 30-40 are familiar. I measured hips too and that kept moving when scale didn’t.
Did you change anything at week 40? I had a similar jump after a vacation and more walking.
NCT04184622 had 2539 people and arms up to 15 mg over 72 weeks. The raw data doesn’t give outcomes, but it reminds me how long trials run.
I’ve wondered about trial timelines too. My own chart looked like a staircase, not a straight line.
61 weeks of tracking now. Scale down 21%, waist down 5.5 inches. Fasting insulin went from 21 to 14, but that didn't show up until around week 50.
hs-CRP dropped early and stayed lower, which was the opposite pattern. The weird part: weeks 44-52 the scale barely moved while waist and resting heart rate both improved. Daily weigh-ins made me nuts, so measurements went monthly instead.
Your 17.2 at week 52 seems plausible if you're still in the lag phase — some of this stuff just lags. Trying not to read too much into one lab draw.
The staircase thing matches my log. I had three weeks flat, then a 4 lb drop, then flat again.
What was your hs-CRP start? Mine barely budged until I hcanged my sleep.
My fasting insulin sat at 19 for like 9 months while my waist went from 37 to 33. It finally dropped to 11 after I stopped eating after 7pm and walked 20 min after dinner. Weird part: scale didn't move that month.
So maybe insulin follows waist/visceral fat and sleep more than scale. Do you track sleep or late meals? That was the swith for me.
At week 52 and 38 lbs down, my tape was the only thing moving during a 10-week scale stall. I went down one scrub size while weight was identical. For me, salty Friday dinners and 5-hour sleep made my Monday fasting labs look worse. Have you checked where you carry fat vs total?
My visceral estimate dropped first, then insulin followed months later.
The change that moved my labs wasn't the big loss, it was boring weekend consistency. Over 52 weeks I lost about 20%, but insulin only went from 21 to 14 after I logged Saturday and Sunday like weekdays.
I wasn't eating crazy, but restaurant meals and alcohol kept me at maintenance two days a week. Once I capped it to one meal out and added a 30-min walk after, my fasting number finally budged.
Also my scale stalled for 7 weeks around week 40, then dropped 5 lbs in 10 days. Labs and tape lag in weird ways. Are your weekends tighter or looser than weekdays?
I'd push back a little on expecting fasting insulin to track scale loss neatly.
Mine was 16 at 25 lbs down and still 15 at 45 lbs down; it only fell after my sleep went from 5.5 to 7 hours. Stress and crappy sleep kept it flat. Track waking heart rate or sleep for two weeks, not jst labs. Sometimes the number is late, not broken.
Sleep was my weird one — I averaged 5.5 hours a night for the better part of a year and my fasting insulin just sat there around 19 while I was visibly shrinking. Around month 9 I started actually getting 7 to 7.5 and it slid to 13 by month 13, with my weight basically flat that entire stretch.
Nobody tells you the labs might respond to the sleep before the fat.
My gut on yours is that 38 lbs over 52 weeks is a legit win and insulin is just slower and lumpier than the scale — mine bounced between 15 and 18 for a while before it budged at all. What's your sleep been like, and are you eating close to bedtime? Those were the two levers I ignored for my whole first year.
I quit weighing on Saturdays and Sundays for a month and it did more for my head than any food change. Monday I'd be up 3-4 lbs from restaurant sodium, back down by Wednesday, and I used to think I'd blown the week when it was just water.
If weeks 30-40 were flat, check your Sunday morning number before you change anything.
Triglycerides and CRP both heading the right direction while insulin just parks there — bodies are rude about timing.
Old jeans are the honest judge. Mine went from can't-button to need-a-belt before a single lab number moved. Waistbands clock it first.
My fastng insulin was the last thing to move. Weight down 40 lbs, waist 42 to 35, but insulin sat at 16 for like 9 months. Then I added a 20-min walk after dinner most nights and started lifting twice a week, and next draw was 10. Not saying that's causal, but the scale and tape moved way before that number.
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